If applying to feet, examine feet to detect skin lesions prior to patch application. During administration, avoid unnecessary contact with items in room (eg, items patient may later have contact with, including bedsheets, horizontal surfaces). Use of a face mask and protective glasses are also recommended during application. Keep patch in sealed pouch until immediately before use patch may then be applied to dry, intact skin using nitrile gloves (latex gloves should not be used). The treatment area and surrounding 1 to 2 cm should be anesthetized with a topical anesthetic prior to patch application keep the local anesthetic in place until the skin is anesthetized and then remove with a dry wipe cleanse area again with soap/water and dry thoroughly. Prior to application, the treatment area should be cleansed with mild soap and water and dried thoroughly. If necessary, excessive hair present on and surrounding the treatment area may be clipped (not shaved). May cut patch (prior to removing the protective release liner) to match size/shape of treatment area. The treatment area must be identified and marked by the health care provider. Do not use with a heating pad.Ĩ% product (Qutenza): Patch should only be applied by a health care provider in a well-ventilated area. Do not use within 1 hour prior to a bath or immediately after bathing. May cut patch to desired size prior to removing the film (product specific). Remove protective film prior to application. ≤0.05% products: Apply patch externally to clean and dry affected area. If applying cream to hands, wait 30 minutes before washing hands. Wash hands with soap and water immediately after applying (unless hands are part of the treatment area). Gently rub into painful area until thoroughly absorbed. Topical products (cream, gel, liquid, lotion): Avoid contact with eyes and mucous membranes. Product strength 0.05%: Adolescents ≥16 years: Topical: Allevess patch: Apply 1 patch to affected area may change patch 1 to 2 times daily Administration Salonpas Pain Relieving Hot Patch (0.025%): Apply 1 patch to affected area for up to 8 hours may change patch up to 3 to 4 times daily Releevia MC (0.0375%), Renovo (0.0375%): Apply 1 patch to affected area may change patch 1 to 2 times daily maximum daily dose: 3 patches/ day MenCaps (0.0225%): Apply 1 patch to affected area for up to 8 hours may change patch up to 3 times daily MaC (0.0375%): Apply 1 patch to affected area for up to 8 hours change patch 2 to 3 times/day maximum daily dose: 4 patches/24 hours Patch: Note: With OTC products, approved ages and uses may vary consult product specific labeling. Lotion 0.025% (DiabetAid Tingling and Pain Relief) Children ≥2 years and Adolescents: Topical: Apply to affected area not more than 3 to 4 times/day Muscle ache and joint pain, minor: Topical: Area should be pretreated with a topical anesthetic prior to patch application. Treatment may be repeated ≥3 months as needed for return of pain (do not apply more frequently than every 3 months). Up to 4 patches may be applied in a single application. Neuropathic pain: Topical: Patch (Qutenza): Apply patch to most painful area for 60 minutes. Topical patch (capsaicin 8%): Systemic absorption is transient and low (5 consecutive days (product specific). The functional link between substance P and the capsaicin receptor, TRPV1, is not well understood. In arthritis, capsaicin induces release of substance P, the principal chemomediator of pain impulses from the periphery to the CNS, from peripheral sensory neurons after repeated application, capsaicin depletes the neuron of substance P and prevents reaccumulation. Transient Receptor Potential Vanilloid 1 (TRPV1) AgonistĬapsaicin, a transient receptor potential vanilloid 1 receptor (TRPV1) agonist, activates TRPV1 ligand-gated cation channels on nociceptive nerve fibers, resulting in depolarization, initiation of action potential, and pain signal transmission to the spinal cord capsaicin exposure results in subsequent desensitization of the sensory axons and inhibition of pain transmission initiation.Salonpas Hot: 0.025% (3s) ĭetailed Capsaicin topical dosage information Brand Names: U.S. Zostrix Natural Pain Relief: 0.033% (56.6 g) Last updated on Jun 9, 2023.Įxcipient information presented when available (limited, particularly for generics) consult specific product labeling.
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